GD真人

检验科许颖教授团队荣获四川省医学会2019年度优秀论文奖

2018-12-31检验科

2019nian12yue30ri,sichuanshengyixuehuiguanfangwangzhangongshile“sichuanshengyixuehuigdzhenren2019nianduyouxiulunwenheqingnianyouxiulunwennijianglunwendegongshi”,diyigdzhenrenjianyankexuyingjiaoshoutuanduibaosongdeyuanchuangxingxueshulunzhu“protective effects of flagellin a n/c against radiation-induced nlr pyrin domain containing 3 inflammasome-dependent pyroptosis in intestinal cells”jingpingxuanronghuo2019nianduyouxiulunwenjiang。


xuyingjiaoshouweilunwentongxunzuozhe,wudongminghehanrongweigongtongdiyizuozhe。gaiwenfabiaozaifangshezhongliuxuetopqikan《international journal of radiation oncology • biology • physics》(2018;101(1):107-117)(jcr 1qu,2018nianif=6.203),gaizazhiweimeiguofangshezhongliuxuehuiguanfangqikan,yeneichengwei“hongpizazhi”,zi1975nianchuangkanyilai,zhuyaojujiaoyufenzifusheshengwuxuejizhongliufangliaoxiangguanlinchuangyanjiudengchuangxinxingyanjiu、jishukaifahelinchuangyingyong。

该研究创新性地揭示了细胞焦亡在辐射性炎性损伤中的分子机制,阐述flagellinA N/C蛋白介导的焦亡抑制在放射性肠炎中的潜在治疗作用,从而为辐射性损伤机制研究及靶向治疗探索了一条新的可能策略。Flagellin A N/C蛋白为该团队具有自主知识产权的抗辐射药物,已授权发明专利2项,围绕该蛋白的前期研究已分别在《Vaccine》《Radiation Research》《Oncology Reports》杂志发表SCI论文3篇。该研究得到了国家自然科学基金、四川省教育厅科研创新团队及成都医学院科研创新团队等项目的支持,在本论文的基础上,许颖教授团队进一步获批国家自然科学基金面上项目1项,四川省科技厅项目2项。


许颖教授简介

GD真人xuying,jiaoshou/zhurenjishi,shuodao,xianrenchengdouyixueyuankejichufuchuzhang、chengdouyixueyuandiyigdzhenrenjianyanke(sichuanshengjiajiyixuezhongdianxueke—linchuangjianyanzhenduanxue)zhuren,ruidiankaluolinsikayixueyuanboshihou。huopiweidishipisichuanshengxueshuhejishudaitourenhoubeirenxuan,dishierpisichuanshengweishengtingxueshuhejishudaitouren,sichuanshengweishengjiankanglingjunrencai。danrenzhongguoweishengwuxuehuilinchuangweishengwuxuezhuanyeweiyuanhuiqingnianweiyuanhuifuzhurenweiyuan、zhongguokangaixiehuizhongliulinchuangjianyanyubansuizhenduanzhuanyeweiyuanhuichangwuweiyuan,sichuanshengyixuehuijianyanzhuanyeweiyuanhuifuzhurenweiyuan、sichuanshengkangfuyixuehuijianyanzhuanweihuizhurenweiyuandengxueshuzhiwu。zhuchiguojiazirankexuejijin2xiang、shengbujiheshengtingjiketi10yuxiang。fuzedekeyantuanduihuopisichuanshengshengshugaoxiaokeyanchuangxintuanduijichengdouyixueyuankeyanchuangxintuanduijianshe。fabiaokeyanlunwen60yupian,qizhong,yidiyizuozhejitongxunzuozhezai《international journal of radiation oncology • biology • physics》、《cell death & disease》、《international journal of cancer》dengguojiqikanfabiaoscilunwen13pian,shouquanguojiafamingzhuanli4xiang。zuoweidiyiwanchengrenhuoshengshijiyixuekejijiangge1xiang。zhuyaocongshi: 1、zhongliuzhuanyifenzijizhijibiaozhiwuyanjiu;2、fushexingxibaojiaowangfenzijizhijibaxiangganyucelve;3、weishengwunaiyaojizhi。

(jianyanke)

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